Deacylation studies on furanose triesters using an immobilized lipase: synthesis of a key precursor for bicyclonucleosides.

نویسندگان

  • Ashok K Prasad
  • Neerja Kalra
  • Yogesh Yadav
  • Rajesh Kumar
  • Sunil K Sharma
  • Shamkant Patkar
  • Lene Lange
  • Jesper Wengel
  • Virinder S Parmar
چکیده

Lipozyme TL IM immobilized on silica catalyses the deacylation of 4-C-acyloxymethyl-3,5-di-O-acyl-1,2-O-(1-methylethylidene)-beta-L-threo-pentofuranose to form 3,5-di-O-acyl-4-C-hydroxymethyl-1,2-O-(1-methylethylidene)-alpha-d-xylo-pentofuranose in a highly selective and efficient manner.

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عنوان ژورنال:
  • Chemical communications

دوره 25  شماره 

صفحات  -

تاریخ انتشار 2007